Description

4,4,5,5-Tetramethyl-2-[2-(2-Methylpropyl)-Phenyl]-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound is valued for its stability and reactivity, serving as a critical intermediate in the synthesis of complex organic molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for cross-coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl motifs found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific boronic ester functionalities.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Chemical Biology Probes: Serves as a building block for creating tagged molecules and bioconjugates used in diagnostic and research applications.
• Catalyst Ligand Synthesis: Utilized in the preparation of sophisticated ligand systems for transition metal catalysis.
• Custom Chemical Synthesis: A versatile reagent for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[2-(2-Methylpropyl)-Phenyl]-1,3,2-Dioxaborolane
CAS No.	1869934-28-0
Molecular Formula	C16H25BO2
Molecular Weight	260.18 g/mol
Synonyms	2-(2-Isobutylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2-(2-Methylpropyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Isobutylphenyl)boronic acid pinacol ester; 2-(2-Isobutylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 1869934-28-0; Isobutylphenyl boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[2-(2-Methylpropyl)-Phenyl]-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to prevent oxidation and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.