Description

2-(1-Cyclopropylvinyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block, specifically a vinyl boronic ester, essential for modern synthetic chemistry. Its core value lies in enabling Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex carbon-carbon bonds with high efficiency and selectivity. This compound is primarily needed by research institutions and pharmaceutical/agrochemical companies for the synthesis of novel organic molecules, including active pharmaceutical ingredients (APIs) and advanced materials. CAS No. 1867923-49-6.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Research: Used to create novel herbicides, fungicides, and insecticides by introducing the cyclopropylvinyl moiety into target structures.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic electronic materials.
• Academic & R&D Laboratories: A versatile building block for methodological development in organic synthesis and catalysis studies.
• Chemical Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and complex natural product analogs.

Basic Information

Product Name	2-(1-Cyclopropylvinyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1867923-49-6
Molecular Formula	C₁₁H₁₉BO₂
Molecular Weight	194.08 g/mol
Synonyms	1-Cyclopropylethylene Pinacol Boronate; (1-Cyclopropylethylidene)boronic Acid Pinacol Ester; 2-(1-Cyclopropylethylidene)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Cyclopropylvinylboronic Acid Pinacol Ester; Vinylboronic Acid Pinacol Ester Cyclopropyl Derivative; B-(1-Cyclopropylethylidene)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-(1-Cyclopropylvinyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. Each lot undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC analysis, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.