Description

3-Oxa-6-Azabicyclo[3.1.1]Heptane Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique bridged bicyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and neurological disorder therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in cutting-edge drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Organic Synthesis Reagent: Used in research-scale and pilot-scale organic reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Process Development: Employed in the optimization and scale-up of synthetic routes for new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for methodological development and the study of heterocyclic chemistry.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	3-Oxa-6-Azabicyclo[3.1.1]Heptane Hydrochloride
CAS No.	1860028-23-4
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	3-Oxa-6-azabicyclo[3.1.1]heptane, hydrochloride; 6-Azabicyclo[3.1.1]heptan-3-one oxime hydrochloride (related precursor); Bicyclo[3.1.1]heptane, 3-oxa-6-aza-, hydrochloride; 3-Oxa-6-azabicyclo[3.1.1]heptane HCl; 1860028-23-4; 3-Oxa-6-azabicyclo[3.1.1]heptane monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Oxa-6-Azabicyclo[3.1.1]Heptane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.