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3-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid, Pinacol Ester CAS NO 1860005-05-5
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CAS No.:1860005-05-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron building block, essential for modern cross-coupling reactions. Its core value lies in enabling the efficient and selective construction of complex molecular architectures, which is critical for research and development in advanced chemistry. This compound is primarily needed by pharmaceutical researchers, agrochemical developers, and material scientists for applications in drug discovery, catalyst design, and the synthesis of functional organic molecules.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
- Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by constructing complex aromatic scaffolds.
- Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
- Chemical Synthesis: Enables the formation of carbon-carbon bonds to create complex, functionalized biaryl and heterobiaryl compounds.
- Ligand & Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
- Academic & Industrial R&D: A versatile reagent for exploratory chemistry in both university laboratories and corporate R&D centers.
Basic Information
| Product Name | 3-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid, Pinacol Ester |
| CAS No. | 1860005-05-5 |
| Molecular Formula | C16H22BClO3 |
| Molecular Weight | 308.61 g/mol |
| Synonyms | [3-Chloro-4-(cyclopropylmethoxy)phenyl]boronic acid pinacol ester; 3-Chloro-4-(cyclopropylmethoxy)benzeneboronic acid pinacol ester; (3-Chloro-4-(cyclopropylmethoxy)phenyl)boronic acid pinacol ester; Pinacol [3-chloro-4-(cyclopropylmethoxy)phenyl]boronate; Boronic acid, B-[3-chloro-4-(cyclopropylmethoxy)phenyl]-, 1,1-dimethylethyl ester; 3-Chloro-4-cyclopropylmethoxyphenylboronic acid pinacol ester; CAS 1860005-05-5 |
| EINECS | Contact for details |
Quality Control
Our 3-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Assay | ≥ 95.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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