Description

3-Ethynyl-2-Fluorobenzaldehyde is a high-value, multi-functional aromatic aldehyde building block characterized by its ethynyl and fluorine substituents. This compound matters for its role as a critical intermediate in modern synthetic chemistry, enabling the construction of complex molecular architectures through reactions like Sonogashira coupling and aldehyde functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A versatile reagent for Sonogashira cross-coupling reactions, click chemistry, and other aldehyde-based transformations in academic and industrial laboratories.
• Ligand & Catalyst Development: Utilized for constructing complex chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Ethynyl-2-Fluorobenzaldehyde
CAS No.	1851952-10-7
Molecular Formula	C9H5FO
Molecular Weight	148.14 g/mol
Synonyms	2-Fluoro-3-ethynylbenzaldehyde; 3-Ethynyl-2-fluorobenzenecarboxaldehyde; 2-Fluorobenzaldehyde, 3-ethynyl-; 3-Ethynyl-2-fluorobenzaldehyde; 1851952-10-7
EINECS	Contact for details

Quality Control

Our 3-Ethynyl-2-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.