Description

tert-Butyl n-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Propyl]Carbamate is a high-purity, protected amine boronic ester building block designed for advanced organic synthesis. This compound matters for its role as a key intermediate in the construction of complex molecules, particularly through cross-coupling reactions like the Suzuki-Miyaura coupling. Pharmaceutical researchers and fine chemical manufacturers need it for the efficient development of active pharmaceutical ingredients (APIs), agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester coupling partner for forming carbon-carbon bonds in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides.
• Material Science Research: Employed in the creation of organic electronic materials, polymers, and ligands for catalysis.
• Peptide Modification & Conjugation: Facilitates the site-specific labeling or functionalization of peptides and proteins.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	tert-Butyl n-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Propyl]Carbamate
CAS No.	1850305-80-4
Molecular Formula	C14H28BNO4
Molecular Weight	285.19 g/mol
Synonyms	Boc-3-aminopropyl MIDA boronate; tert-Butyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl)carbamate; 2-[3-[(2-Methylpropan-2-yl)oxycarbonylamino]propyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; N-Boc-3-aminopropylboronic acid MIDA ester; 3-((tert-Butoxycarbonyl)amino)propylboronic acid pinacol ester; (3-((tert-Butoxycarbonyl)amino)propyl)boronic acid pinacol ester; Boc-NH-(CH2)3-Bpin
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Propyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.