Description

tert-Butyl 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethylcarbamate is a high-purity, protected amine boronic ester building block essential for modern synthetic chemistry. This compound is valued for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex biaryl or heterobiaryl linkages.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs and OFETs.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Academic & Industrial R&D: A versatile reagent for methodological development in cross-coupling chemistry and the construction of complex natural product analogs.

Basic Information

Product Name	tert-Butyl 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethylcarbamate
CAS No.	1850305-79-1
Molecular Formula	C₁₃H₂₆BNO₄
Molecular Weight	271.16 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)ethylboronic acid pinacol ester; N-Boc-2-aminoethylboronic acid pinacol ester; tert-Butyl N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethyl]carbamate; Boc-NH-CH2-CH2-Bpin; (2-((tert-Butoxycarbonyl)amino)ethyl)boronic acid pinacol ester; 2-(Boc-amino)ethylboronic acid pinacol ester; 1850305-79-1
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Ethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.