Description

1-(4-Bromo-3-(Chloromethyl)Phenyl)Ethan-1-One is a high-purity, multi-functional organic building block featuring both bromo and chloromethyl substituents on an aromatic ketone core. This compound is critical for advanced organic synthesis, enabling the construction of complex molecular architectures through selective cross-coupling and nucleophilic substitution reactions. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its reactive halogen sites for structural diversification.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules or affinity probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(4-Bromo-3-(Chloromethyl)Phenyl)Ethan-1-One
CAS No.	1844064-90-9
Molecular Formula	C9H8BrClO
Molecular Weight	247.52 g/mol
Synonyms	1-(4-Bromo-3-(chloromethyl)phenyl)ethanone; 4'-Bromo-3'-(chloromethyl)acetophenone; 1-Acetyl-4-bromo-3-chloromethylbenzene; 2-Bromo-5-acetylbenzyl chloride; 4-Bromo-3-(chloromethyl)acetophenone; α-Chloro-4'-bromo-3'-methylacetophenone; Ethanone, 1-[4-bromo-3-(chloromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Bromo-3-(Chloromethyl)Phenyl)Ethan-1-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.