Description

2-(4-(Methoxycarbonyl)Bicyclo[2.2.2]Octan-1-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a rigid bicyclo[2.2.2]octane scaffold. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry where its structure can impart desirable pharmacokinetic properties. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those requiring a rigid, three-dimensional core structure.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, including ester hydrolysis, amide coupling, and derivatization of the carboxylic acid group.
• Material Science Research: Potential monomer or additive for creating novel polymers with specific thermal or mechanical properties derived from the bicyclic unit.

Basic Information

Product Name	2-(4-(Methoxycarbonyl)Bicyclo[2.2.2]Octan-1-Yl)Acetic Acid
CAS No.	1838668-75-9
Molecular Formula	C13H18O4
Molecular Weight	238.28 g/mol
Synonyms	2-[4-(Methoxycarbonyl)bicyclo[2.2.2]octan-1-yl]acetic acid; 1-Bicyclo[2.2.2]octaneacetic acid, 4-(methoxycarbonyl)-; Methyl 4-(carboxymethyl)bicyclo[2.2.2]octane-1-carboxylate; (4-(Methoxycarbonyl)bicyclo[2.2.2]oct-1-yl)acetic acid; CAS 1838668-75-9
EINECS	Contact for details

Quality Control

Our 2-(4-(Methoxycarbonyl)Bicyclo[2.2.2]Octan-1-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.