Description

5-Bromopyridine-3-Boronic Acid Mida Ester is a high-value, protected boronic acid derivative designed for advanced synthetic chemistry. This compound is crucial for enabling robust and selective cross-coupling reactions, particularly in the synthesis of complex heterocyclic molecules. It is primarily utilized by pharmaceutical and agrochemical R&D teams, as well as by fine chemical manufacturers, for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyridine and bipyridine scaffolds.
• Suzuki-Miyaura Cross-Coupling: The MIDA ester protecting group enhances stability and handling, making this reagent ideal for iterative cross-coupling strategies in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Useful for creating tagged molecules and bioconjugates for target identification and biochemical assays.

Basic Information

Product Name	5-Bromopyridine-3-Boronic Acid Mida Ester
CAS No.	1835721-30-6
Molecular Formula	C9H8BBrN2O4
Molecular Weight	298.89 g/mol
Synonyms	5-Bromo-3-pyridylboronic acid MIDA ester; (5-Bromopyridin-3-yl)boronic acid MIDA ester; 2-(5-Bromopyridin-3-yl)-1,3,2-dioxaborinan-4,6-dione; 5-Bromo-3-pyridylboronic acid N-methyliminodiacetic acid ester; 5-Bromo-3-pyridyl MIDA boronate; 5-Bromo-3-pyridyl-B(MIDA); 1835721-30-6; 5-Bromopyridine-3-boronic acid MIDA ester
EINECS	Contact for details

Quality Control

Our 5-Bromopyridine-3-Boronic Acid Mida Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.