Description

2-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis.
• Ligand & Catalyst Development: Employed in the preparation of novel boron-containing ligands and organometallic catalysts.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke organic compounds.

Basic Information

Product Name	2-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid
CAS No.	1824647-98-4
Molecular Formula	C10H12BClO3
Molecular Weight	226.46 g/mol
Synonyms	[2-Chloro-4-(cyclopropylmethoxy)phenyl]boronic acid; (2-Chloro-4-(cyclopropoxymethyl)phenyl)boronic acid; 2-Chloro-4-cyclopropylmethoxyphenylboronic acid; B-[2-Chloro-4-(cyclopropylmethoxy)phenyl]boronic acid; 2-Chloro-4-(cyclopropylmethoxy)benzeneboronic acid; CPMPBA; CAS 1824647-98-4
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Cyclopropylmethoxy)Phenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry-standard analytical methods, and specifications can be tailored to meet specific project requirements for pharmaceutical development (GMP standards) or advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.