Description

3',4'-Dichloro-5'-(trifluoromethoxy)acetophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated and trifluoromethoxy-substituted aromatic structure. This compound is of significant commercial importance for its role in the synthesis of complex, biologically active molecules, offering a versatile building block for medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic core and halogen substituents for tailored material properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and inhibitors for studying enzyme function and cellular pathways in academic and industrial R&D.

Basic Information

Product Name	3',4'-Dichloro-5'-(trifluoromethoxy)acetophenone
CAS No.	1823541-26-9
Molecular Formula	C9H5Cl2F3O2
Molecular Weight	273.04 g/mol
Synonyms	1-[3,4-Dichloro-5-(trifluoromethoxy)phenyl]ethan-1-one; 3,4-Dichloro-α,α,α-trifluoro-5-methoxyacetophenone; 3,4-Dichloro-5-(trifluoromethoxy)acetophenone; 3',4'-Dichloro-5'-(trifluoromethoxy)acetophenone; 3,4-Dichloro-α,α,α-trifluoro-5-methoxyacetophenone; Acetophenone, 3',4'-dichloro-5'-(trifluoromethoxy)-; 3,4-Dichloro-5-trifluoromethoxyacetophenone
EINECS	Contact for details

Quality Control

Our 3',4'-Dichloro-5'-(trifluoromethoxy)acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.