Description

1-Chloro-2,2,2-Trifluoroethyl Acetate is a specialized fluorinated organic ester, serving as a versatile building block and intermediate in advanced chemical synthesis. Its molecular structure, featuring both chloro and trifluoromethyl groups, provides unique reactivity and physicochemical properties critical for developing high-value compounds. This product is essential for research and production in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating biological activity and stability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to efficacy and environmental persistence.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and esterification reactions to introduce the 1-chloro-2,2,2-trifluoroethyl moiety into more complex molecular architectures.
• Material Science Precursor: Acts as a starting material for synthesizing fluorinated polymers, coatings, and liquid crystals with specialized surface properties and chemical resistance.
• Research & Development: Utilized in academic and industrial R&D laboratories for exploring new synthetic pathways and creating novel fluorinated compounds.

Basic Information

Product Name	1-Chloro-2,2,2-Trifluoroethyl Acetate
CAS No.	1823369-75-0
Molecular Formula	C4H4ClF3O2
Molecular Weight	176.52 g/mol
Synonyms	Acetic Acid, 2-Chloro-1,1,1-trifluoroethyl Ester; 2-Chloro-1,1,1-trifluoroethyl Acetate; 1,1,1-Trifluoro-2-chloroethyl Acetate; CF3CHClOCOCH3; α-Chloro-α,α,α-trifluoroethyl Acetate
EINECS	Contact for details

Quality Control

Our 1-Chloro-2,2,2-Trifluoroethyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 8°C for extended stability. The container should be kept tightly sealed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.40 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.