Description

1,3-Difluoroprop-2-Yl Trifluoroacetate is a specialized fluorinated building block and reagent of significant interest in advanced organic synthesis. This compound matters for its role in introducing fluorinated motifs, which are critical for modulating the physicochemical and metabolic properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty materials and fine chemicals.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting improved bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Material Science: Serves as a precursor or modifying agent in the synthesis of fluorinated polymers, coatings, and specialty materials with unique surface properties.
• Organic Synthesis Reagent: Employed as a versatile reagent in academic and industrial laboratories for nucleophilic substitution and esterification reactions to construct complex fluorinated architectures.
• Liquid Crystal & Electronic Chemicals: Potential use in the synthesis of fluorinated components for liquid crystal displays (LCDs) and other electronic materials requiring specific dielectric properties.

Basic Information

Product Name	1,3-Difluoroprop-2-Yl Trifluoroacetate
CAS No.	1823362-61-3
Molecular Formula	C5H3F5O2
Molecular Weight	190.07 g/mol
Synonyms	2,2-Difluoro-3-(trifluoroacetoxy)propane; 3,3-Difluoro-2-(trifluoroacetoxy)propane; 1,3-Difluoropropan-2-yl trifluoroacetate; Trifluoroacetic Acid 1,3-Difluoroprop-2-yl Ester; 2-(Trifluoroacetoxy)-1,3-difluoropropane; 1,3-Difluoro-2-propyl trifluoroacetate
EINECS	Contact for details

Quality Control

Our 1,3-Difluoroprop-2-Yl Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its highly volatile nature, keep the container tightly sealed when not in use and away from heat, sparks, and open flame. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.