Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,2,3,6-Tetrahydropyridine is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl/heteroaryl halides and boronic esters, a fundamental reaction in complex molecule assembly.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and probes for studying biological systems and mechanisms.
• Library Synthesis for High-Throughput Screening: A valuable reagent for generating diverse compound libraries to identify new bioactive molecules.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,2,3,6-Tetrahydropyridine
CAS No.	1823117-23-2
Molecular Formula	C15H26BNO2
Molecular Weight	263.19 g/mol
Synonyms	1,2,3,6-Tetrahydro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydropyridin-5-ylboronic acid pinacol ester; 5-(Pinacolatoboryl)-1,2,3,6-tetrahydropyridine; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; 5-Boronic acid, 1,2,3,6-tetrahydro-, pinacol ester, pyridine-5-boronic acid pinacol ester (1,2,3,6-tetrahydro-)
EINECS	Contact for details

Quality Control

Our 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,2,3,6-Tetrahydropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.