Description

2-(2-Amino-3-Fluorophenyl)-2-Oxoacetaldehyde is a high-value fluorinated aromatic building block featuring both an amino and a reactive oxoaldehyde functional group. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex heterocycles and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for developing novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Heterocyclic Chemistry: The reactive aldehyde and amine groups enable its use in constructing complex heterocyclic scaffolds like quinazolines, quinoxalines, and fused ring systems.
• Chemical Biology & Proteomics: Used in the development of chemical probes and affinity tags due to its reactive handles for bioconjugation.
• Material Science Research: Serves as a monomer or cross-linker in the development of specialty polymers and advanced organic materials.
• Contract Research & Development (CRO/CMO): Supplied to custom synthesis and process development organizations for client-specific projects.

Basic Information

Product Name	2-(2-Amino-3-Fluorophenyl)-2-Oxoacetaldehyde
CAS No.	1823040-56-7
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	2-Oxo-2-(2-amino-3-fluorophenyl)acetaldehyde; 2-Amino-3-fluorobenzoylformaldehyde; 2-(2-Amino-3-fluorophenyl)-2-oxoethanal; 3-Fluoro-2-aminophenylglyoxal; α-Oxo-2-amino-3-fluorophenylacetaldehyde; Glyoxal, 2-(2-amino-3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-(2-Amino-3-Fluorophenyl)-2-Oxoacetaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from HPLC, NMR, and MS, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the sealed container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.