Description

tert-Butyl (3Ar,7Ar)-1,2,3,3A,4,5,7,7A-Octahydropyrrolo[2,3-C]Pyridine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex, fused bicyclic structure. This compound is a critical building block in modern organic synthesis, enabling the construction of sophisticated nitrogen-containing heterocycles. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for creating new chemical entities with potential therapeutic value.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex, polycyclic nitrogen heterocycles common in many bioactive molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry's outsourced R&D and production needs.
• Academic Research: Used in universities and institutes for methodological development in synthetic organic chemistry and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl (3Ar,7Ar)-1,2,3,3A,4,5,7,7A-Octahydropyrrolo[2,3-C]Pyridine-6-Carboxylate
CAS No.	1821737-93-2
Molecular Formula	C14H22N2O2
Molecular Weight	250.34 g/mol
Synonyms	tert-Butyl octahydropyrrolo[2,3-c]pyridine-6-carboxylate; 1,1-Dimethylethyl (3aR,7aR)-hexahydro-1H-pyrrolo[2,3-c]pyridine-6(2H)-carboxylate; (3aR,7aR)-tert-Butyl hexahydro-1H-pyrrolo[2,3-c]pyridine-6(2H)-carboxylate; tert-Butyl (3aR,7aR)-octahydro-1H-pyrrolo[2,3-c]pyridine-6-carboxylate; Bicyclic pyrrolopyridine ester intermediate; CAS 1821737-93-2
EINECS	Contact for details

Quality Control

Our tert-Butyl (3Ar,7Ar)-1,2,3,3A,4,5,7,7A-Octahydropyrrolo[2,3-C]Pyridine-6-Carboxylate is manufactured under strict quality management systems. All batches undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.