Description

5-(Bromomethyl)-2-Fluorobenzaldehyde is a versatile and highly functionalized aromatic aldehyde building block. Its molecular structure, featuring both a reactive bromomethyl group and an aldehyde moiety on a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors. It enables the synthesis of novel active ingredients through efficient cross-coupling and further functionalization reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its dual reactive sites.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or affinity probes for studying biological processes and target engagement.
• Custom Synthesis and Scale-Up: A fundamental building block for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis for clients.

Basic Information

Product Name	5-(Bromomethyl)-2-Fluorobenzaldehyde
CAS No.	1820717-85-8
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	2-Fluoro-5-(bromomethyl)benzaldehyde; 5-Bromomethyl-2-fluorobenzaldehyde; 2-Fluorobenzaldehyde, 5-(bromomethyl)-; 5-(Bromomethyl)-2-fluorobenzenecarboxaldehyde; (5-Bromomethyl-2-fluorophenyl)methanal; 1820717-85-8; 5-Bromomethyl-2-fluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)-2-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our commitment to quality assurance supports your R&D and production needs with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.