Description

(5-(4-Fluorophenyl)Thiophen-2-Yl)(5-Iodo-2-Methylphenyl)Methanol is a sophisticated, multi-functional organic intermediate of significant interest in advanced chemical synthesis. Its complex molecular architecture, featuring fluorophenyl, thiophene, iodophenyl, and methanol groups, makes it a valuable building block for creating novel compounds with tailored properties. This product is primarily targeted at research and development teams within the pharmaceutical, agrochemical, and materials science industries who require high-purity, structurally complex intermediates for their discovery and process development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated aromatic structure for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Functional Material Synthesis: Employed in the creation of organic electronic materials, such as components for OLEDs (Organic Light-Emitting Diodes) or semiconductors, due to the conjugated thiophene system.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes, where the iodine atom can serve as a handle for further modification (e.g., radioiodination).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) and fine chemical companies for custom synthesis projects requiring this specific scaffold.

Basic Information

Product Name	(5-(4-Fluorophenyl)Thiophen-2-Yl)(5-Iodo-2-Methylphenyl)Methanol
CAS No.	1818268-45-9
Molecular Formula	C18H14FIOS
Molecular Weight	424.27 g/mol
Synonyms	[5-(4-Fluorophenyl)-2-thienyl](5-iodo-2-methylphenyl)methanol; (5-(4-Fluorophenyl)thiophen-2-yl)(5-iodo-2-methylphenyl)methanol; (5-Iodo-2-methylphenyl)[5-(4-fluorophenyl)-2-thienyl]methanol; 1-(5-Iodo-2-methylphenyl)-1-[5-(4-fluorophenyl)thiophen-2-yl]methanol; CAS 1818268-45-9; 1818268-45-9
EINECS	Contact for details

Quality Control

Our (5-(4-Fluorophenyl)Thiophen-2-Yl)(5-Iodo-2-Methylphenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications such as assay (by HPLC), related substances, and residual solvents, meeting the stringent requirements of research and development applications. Specifications can be aligned with customer-specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and should be handled under inert atmosphere if prolonged exposure is anticipated to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.