Description

Carboxy-Peg2-Sulfonic Acid is a specialized bifunctional PEG linker featuring both a carboxylic acid and a sulfonic acid group, separated by a short polyethylene glycol spacer. This unique structure provides enhanced water solubility and versatile conjugation chemistry, making it a critical intermediate for creating stable, functionalized biomolecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and bioconjugation sectors for developing advanced drug delivery systems, diagnostic reagents, and novel therapeutic agents.

Application

• Bioconjugation Reagent: For coupling peptides, proteins, or antibodies to surfaces, nanoparticles, or other molecules via its carboxylic acid group.
• Drug Delivery System Development: As a hydrophilic linker to improve the solubility and pharmacokinetic properties of prodrugs and active pharmaceutical ingredients (APIs).
• Diagnostic Assay Components: In the synthesis of fluorescent or enzyme-labeled probes for immunoassays and biosensors.
• Surface Modification: To introduce negatively charged sulfonate groups onto materials for enhanced biocompatibility or specific binding properties.
• Polymer Chemistry: As a monomer or cross-linking agent for creating functional hydrogels and smart polymers.
• Affinity Chromatography Ligands: For the immobilization of biomolecules on solid supports used in purification columns.

Basic Information

Product Name	Carboxy-Peg2-Sulfonic Acid
CAS No.	1817735-45-7
Molecular Formula	C7H14O8S
Molecular Weight	258.25 g/mol
Synonyms	2-[2-(2-Carboxyethoxy)ethoxy]ethanesulfonic acid; 3,6,9-Trioxa-2-azadodecan-12-oic acid, 11-sulfo- (related IUPAC forms); PEG2-acid-sulfonic acid; Carboxy-PEG2-SO3H; HOOC-PEG2-Sulfonic Acid; 11-Sulfo-3,6,9-trioxa-2-azadodecan-12-oic acid; Sulfopropionic acid-PEG2-acid
EINECS	Contact for details

Quality Control

Our Carboxy-Peg2-Sulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.