Description

T-Butoxycarbonyl-Peg5-Sulfonic Acid is a specialized bifunctional PEG derivative featuring a Boc-protected amine and a terminal sulfonic acid group. This unique structure makes it a versatile building block for creating water-soluble linkers, modifying biomolecules, and engineering functional surfaces. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for developing targeted drug delivery systems, diagnostic agents, and hydrophilic coatings.

Application

• Bioconjugation & Drug Delivery: Serves as a hydrophilic, functionalized linker for attaching targeting ligands, drugs, or imaging agents to proteins, peptides, or nanoparticles.
• Surface Modification: Used to introduce sulfonic acid groups and PEG chains onto material surfaces (e.g., gold, silica) to enhance hydrophilicity, reduce non-specific binding, or create ion-exchange properties.
• Polymer & Dendrimer Synthesis: Acts as a monomer or chain extender for synthesizing functionalized, water-soluble polymers with acid and amine handles for further modification.
• Proteomics Research: Employed in the synthesis of reagents for labeling, crosslinking, or enriching peptides and proteins in analytical workflows.
• Solid-Phase Peptide Synthesis (SPPS): Can be incorporated into peptide sequences to introduce PEGylation sites or charged moieties directly during synthesis.
• Catalyst & Ligand Design: The sulfonic acid group allows for the creation of acid-functionalized ligands or catalysts with improved solubility in aqueous or mixed solvent systems.

Basic Information

Product Name	T-Butoxycarbonyl-Peg5-Sulfonic Acid
CAS No.	1817735-28-6
Molecular Formula	C20H41NO11S
Molecular Weight	503.61 g/mol
Synonyms	Boc-NH-PEG5-Sulfonic Acid; tert-Butyl (1-{2-[2-(2-{2-[2-(2-Sulfoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethyl}carbamate); 2-{2-[2-(2-{2-[2-(2-{[(tert-Butoxy)carbonyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethane-1-sulfonic Acid; Boc-Amino-PEG5-Sulfonic Acid; Boc-PEG5-SO3H; NHBoc-PEG5-Sulfonic Acid; 1-(tert-Butoxycarbonylamino)-3,6,9,12,15-pentaoxaoctadecane-18-sulfonic Acid
EINECS	Contact for details

Quality Control

Our T-Butoxycarbonyl-Peg5-Sulfonic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.