Description

4-(3-Fluorophenyl)-2,4-Dihydro-3H-1,2,4-Triazol-3-One is a high-purity fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its unique triazolone core functionalized with a fluorinated aromatic ring, making it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This product is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the fluorophenyl-triazolone moiety.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme inhibition and protein-ligand interactions in biochemical assays.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced materials requiring specific thermal or optical properties.
• Academic & Contract Research: Essential reagent for methodology development in organic chemistry, including cross-coupling reactions and heterocycle formation studies.

Basic Information

Product Name	4-(3-Fluorophenyl)-2,4-Dihydro-3H-1,2,4-Triazol-3-One
CAS No.	1817687-96-9
Molecular Formula	C8H6FN3O
Molecular Weight	179.15 g/mol
Synonyms	4-(3-Fluorophenyl)-1,2,4-triazol-5(4H)-one; 3H-1,2,4-Triazol-3-one, 4-(3-fluorophenyl)-2,4-dihydro-; 4-(3-Fluorophenyl)-4,5-dihydro-3H-1,2,4-triazol-3-one; 4-(3-Fluorophenyl)-2H-1,2,4-triazol-3(4H)-one; 4-(m-Fluorophenyl)-1,2,4-triazol-5(4H)-one; 1817687-96-9; 4-(3-Fluorophenyl)-1,2,4-triazol-3-one
EINECS	Contact for details

Quality Control

Our 4-(3-Fluorophenyl)-2,4-Dihydro-3H-1,2,4-Triazol-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.