Description

2-Hydroxy-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzaldehyde is a versatile and highly valuable boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery, ligand synthesis, and the development of functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or phenolic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require boronic acid ester chemistry.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, polymers, and metal-organic frameworks (MOFs).
• Chemical Research & Development: An indispensable reagent in academic and industrial labs for palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand and Catalyst Preparation: Employed in the synthesis of sophisticated ligands for catalysis and molecular recognition applications.
• Fluorescent Probe Synthesis: Used as a starting material for developing sensors and imaging agents due to its aldehyde and boronate functional groups.

Basic Information

Product Name	2-Hydroxy-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzaldehyde
CAS No.	1816937-59-3
Molecular Formula	C₁₃H₁₇BO₄
Molecular Weight	248.09 g/mol
Synonyms	4-Formyl-3-hydroxyphenylboronic acid pinacol ester; 2-Hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-hydroxybenzaldehyde; 2-Hydroxy-4-(pinacolatoboryl)benzaldehyde; Salicylaldehyde-4-boronic acid pinacol ester; 4-Borono-2-hydroxybenzaldehyde pinacol ester; (4-Formyl-3-hydroxyphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.