Description

2,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules. Its stability and reactivity profile make it a preferred reagent for constructing pyridine-containing scaffolds in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Material Science: Serves as a monomer or precursor for creating organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds with high selectivity and yield.
• Chemical Biology & Probe Development: Utilized for synthesizing molecular probes and labeled compounds for biological target identification and mechanism studies.
• Academic & Contract Research: A staple reagent in R&D laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	2,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS No.	1815616-21-7
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	2,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dimethylpyridine; 2,3-Dimethyl-4-pyridineboronic acid pinacol ester; 2,3-Dimethylpyridine-4-boronic acid pinacol ester; 4-Borono-2,3-dimethylpyridine pinacol ester; 1815616-21-7; 2,3-Dimethyl-4-(pinacolboryl)pyridine
EINECS	Contact for details

Quality Control

Our 2,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and commercial use. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.