Description

Benzoxazole-6-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative used as a key building block in cross-coupling reactions. This compound matters because it provides a protected, air-stable form of the reactive boronic acid, enabling precise and efficient synthesis of complex heterocyclic architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between the benzoxazole scaffold and various aryl/heteroaryl halides.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of new drug candidates, particularly those containing fused heterocyclic systems.
• Agrochemical Active Ingredient Development: Serves as a building block for novel herbicides, fungicides, and insecticides.
• Material Science & OLED Research: Employed in the synthesis of organic semiconductors, light-emitting materials, and other functional molecules.
• Chemical Biology & Probe Development: Useful for creating tagged molecules and bioconjugates for biological target studies.
• Scale-up Process Chemistry: Suitable for transitioning from laboratory-scale discovery to pilot and commercial manufacturing due to its stability.

Basic Information

Item	Details
Product Name	Benzoxazole-6-Boronic Acid Pinacol Ester
CAS No.	1810038-58-4
Molecular Formula	C15H20BNO3
Molecular Weight	273.14 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoxazole; Benzoxazol-6-ylboronic Acid Pinacol Ester; 2-(Benzoxazol-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazole; Pinacol Benzoxazole-6-boronate
EINECS	Contact for details

Quality Control

Our Benzoxazole-6-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.