Description

2-Methyl-2H-Pyrazolo[3,4-B]Pyridine-5-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is valued for its role in facilitating efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Synthesis: Enables efficient Suzuki-Miyaura cross-coupling reactions to construct complex biaryl and heterobiaryl structures prevalent in modern organic chemistry.
• Academic & Contract Research: Essential reagent for medicinal chemistry and synthetic methodology research in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-Methyl-2H-Pyrazolo[3,4-B]Pyridine-5-Boronic Acid Pinacol Ester
CAS No.	1809889-70-0
Molecular Formula	C13H18BN3O2
Molecular Weight	259.11 g/mol
Synonyms	2-Methyl-2H-pyrazolo[3,4-b]pyridin-5-ylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-2H-pyrazolo[3,4-b]pyridine; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-pyrazolo[3,4-b]pyridine; 2-Methyl-2H-pyrazolo[3,4-b]pyridine-5-boronic acid, pinacol ester; 1809889-70-0; 2-Methylpyrazolopyridine-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-2H-Pyrazolo[3,4-B]Pyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for critical coupling reactions. Certificates of Analysis (COA) with full characterization data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.