Description

1-Bromo-3-Chloro-4-Methyl-2-(Methylthio)Benzene is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where its halogen and thioether groups contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis for cross-coupling and other important organic transformations.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or monomers for conductive polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Bromo-3-Chloro-4-Methyl-2-(Methylthio)Benzene
CAS No.	1809168-68-0
Molecular Formula	C8H8BrClS
Molecular Weight	251.57 g/mol
Synonyms	2-Bromo-4-Chloro-5-Methyl-1-(Methylthio)Benzene; 3-Chloro-1-bromo-4-methyl-2-(methylthio)benzene; Benzene, 1-bromo-3-chloro-4-methyl-2-(methylthio)-; 4-Methyl-2-(methylthio)-1-bromo-3-chlorobenzene; 1-Bromo-3-chloro-4-methyl-2-methylthiobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-4-Methyl-2-(Methylthio)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.