Description

2-Ethoxy-5-Fluoroisonicotinaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde and an ethoxy-fluoro substitution pattern, makes it indispensable for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated pyridine scaffolds.

Basic Information

Product Name	2-Ethoxy-5-Fluoroisonicotinaldehyde
CAS No.	1809157-93-4
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	5-Fluoro-2-ethoxyisonicotinaldehyde; 5-Fluoro-2-ethoxypyridine-4-carboxaldehyde; 4-Pyridinecarboxaldehyde, 5-fluoro-2-ethoxy-; 2-Ethoxy-5-fluoropyridine-4-carbaldehyde; 1809157-93-4; 5-Fluoro-2-ethoxy-4-formylpyridine; 2-Ethoxy-5-fluoro-4-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-5-Fluoroisonicotinaldehyde is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and GC-MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.