Description

1-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[3,2-b]pyridine CAS NO 1807956-37-1 is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions for the synthesis of complex heterocyclic molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of novel therapeutic agents, particularly in oncology and CNS disorders.

Application

• Suzuki-Miyaura Cross-Coupling Reagent: A key reactant for constructing carbon-carbon bonds in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Pharmaceutical Intermediate: Serves as a versatile building block for the development of novel small-molecule drugs targeting various disease pathways.
• Organic Synthesis Research: Used in academic and industrial R&D laboratories for creating complex heterocyclic scaffolds and exploring new chemical spaces.
• Agrochemical Development: Employed in the synthesis of advanced crop protection agents and herbicides requiring specific heterocyclic structures.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, such as OLEDs or conductive polymers, due to its fused ring system.
• Chemical Biology Probe Synthesis: Facilitates the creation of labeled compounds and molecular probes for biological target identification and validation.

Basic Information

Product Name	1-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[3,2-b]pyridine
CAS No.	1807956-37-1
Molecular Formula	C15H21BN2O2
Molecular Weight	272.15 g/mol
Synonyms	1-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[3,2-b]pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-pyrrolo[3,2-b]pyridine; 1-Methyl-1H-pyrrolo[3,2-b]pyridine-6-boronic acid pinacol ester; 1-Methyl-6-(pinacolboryl)-1H-pyrrolo[3,2-b]pyridine; 1-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-azaindole; 1807956-37-1; 1-Methyl-6-boronic acid pinacol ester-1H-pyrrolo[3,2-b]pyridine
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Quality Control

Our 1-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrrolo[3,2-b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.