Description

Bis-Peg4-Sulfonic Acid CAS NO 1807539-08-7 is a high-purity, functionalized polyethylene glycol derivative featuring terminal sulfonic acid groups, making it a versatile bifunctional linker and building block. This compound is critical for introducing water solubility, ionic character, and reactive sites into complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors for developing targeted drug delivery systems, functional polymers, and specialized chemical probes.

Application

• Bioconjugation & ADC Development: Serves as a hydrophilic, charged linker for antibody-drug conjugates (ADCs) and protein modifications to improve solubility and pharmacokinetics.
• Polymer & Material Science: Acts as a monomer or crosslinker for synthesizing ion-conductive polymers, hydrogels, and smart materials with pH-responsive properties.
• Chemical Synthesis: Used as a bifunctional reagent for introducing PEG spacers and sulfonate groups into small molecules, peptides, and other organic compounds.
• Surface Functionalization: Employed to modify nanoparticles, quantum dots, and solid supports to enhance dispersibility in aqueous media and enable further covalent attachment.
• Diagnostic Reagents: Utilized in the design of contrast agents, biosensors, and assay components where water solubility and specific ionic interactions are required.

Basic Information

Product Name	Bis-Peg4-Sulfonic Acid
CAS No.	1807539-08-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,11-Bis(sulfo)-3,6,9-trioxaundecane-1,11-dioic acid; PEG4-disulfonic acid; Tetraethylene glycol disulfonic acid; Bis-sulfonated PEG4; 3,6,9,12-Tetraoxatetradecanedioic acid, 1,14-disulfo-; 1,14-Disulfo-3,6,9,12-tetraoxatetradecanedioic acid
EINECS	Contact for details

Quality Control

Our Bis-Peg4-Sulfonic Acid is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.