Description

m-Peg5-Sulfonic Acid CAS NO 1807505-35-6 is a specialized, high-purity sulfonic acid derivative functionalized with a monodisperse pentaethylene glycol (PEG5) spacer. This compound is engineered to provide a unique combination of water solubility, chemical reactivity, and controlled polarity, making it a critical intermediate for advanced material synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and specialty polymer industries who require precise chemical modifications and linker technologies.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics, where the PEG spacer enhances solubility and pharmacokinetics.
• Bioconjugation Reagent: Used to introduce sulfonic acid groups or PEGylated linkers onto proteins, peptides, and other biomolecules to alter solubility, stability, or detection properties.
• Polymer Modification: Acts as a functional monomer or end-group modifier for creating hydrophilic, anionic, or surfactant-like polymers with specific solution properties.
• Surface Functionalization: Employed to coat or modify material surfaces (e.g., nanoparticles, diagnostic chips) to impart negative charge, anti-fouling characteristics, or specific biorecognition sites.
• Catalyst and Ligand Synthesis: Utilized in the preparation of specialized ligands or catalysts where the PEG-sulfonic acid moiety can influence reactivity and phase-transfer properties.
• Research & Development: A valuable tool in chemical biology and materials science R&D for exploring new linker chemistries and functional group interactions.

Basic Information

Product Name	m-Peg5-Sulfonic Acid
CAS No.	1807505-35-6
Molecular Formula	C14H30O9S
Molecular Weight	398.45 g/mol
Synonyms	m-PEG5-Sulfonic Acid; 2,5,8,11,14-Pentaoxaheptadecane-17-sulfonic Acid; Monomethoxy PEG5 Sulfonic Acid; 17-Methoxy-3,6,9,12,15-pentaoxaheptadecane-1-sulfonic Acid; mPEG5-SO3H; PEG5 Methyl Ether Sulfonic Acid; 1-Methoxy-3,6,9,12,15-pentaoxaheptadecan-17-yl Sulfonate; (17-Methoxy-3,6,9,12,15-pentaoxaheptadecyl)sulfonic Acid
EINECS	Contact for details

Quality Control

m-Peg5-Sulfonic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR for structural confirmation, and titration for functional group analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Titration)	≥ 90%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.