Description

2-Bromo-3,5-Difluorobenzyl Bromide is a versatile and highly reactive benzyl bromide derivative, distinguished by its strategic halogen and fluorine substitution pattern. This compound is a critical pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecules for advanced research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the difluoro motif for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials to modify physical properties.
• Chemical Biology Probes: Useful for the site-specific functionalization of biomolecules or as a scaffold for developing enzyme inhibitors and receptor modulators.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic methodologies.

Basic Information

Product Name	2-Bromo-3,5-Difluorobenzyl Bromide
CAS No.	1807071-26-6
Molecular Formula	C7H4Br2F2
Molecular Weight	289.91 g/mol
Synonyms	1-(Bromomethyl)-2-bromo-3,5-difluorobenzene; (2-Bromo-3,5-difluorophenyl)methyl bromide; 3,5-Difluoro-2-bromobenzyl bromide; alpha,2-Dibromo-3,5-difluorotoluene; Benzene, 1-(bromomethyl)-2-bromo-3,5-difluoro-; 2-Bromo-3,5-difluoro-α-bromotoluene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3,5-Difluorobenzyl Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.