Description

2'-Bromo-3',6'-Difluoroacetophenone is a high-purity, multi-functional halogenated acetophenone derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2'-Bromo-3',6'-Difluoroacetophenone
CAS No.	1807029-26-0
Molecular Formula	C8H5BrF2O
Molecular Weight	235.03 g/mol
Synonyms	1-(2-Bromo-3,6-difluorophenyl)ethan-1-one; 2-Bromo-3,6-difluoroacetophenone; 3',6'-Difluoro-2'-bromoacetophenone; α-Bromo-3,6-difluoroacetophenone; Ethanone, 1-(2-bromo-3,6-difluorophenyl)-; (2-Bromo-3,6-difluorophenyl)methyl ketone
EINECS	Contact for details

Quality Control

Our 2'-Bromo-3',6'-Difluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.