Description

2-Bromo-5-Chloro-4-Fluorobenzaldehyde is a high-purity halogenated benzaldehyde derivative, serving as a critical advanced intermediate in modern organic synthesis. Its multi-halogenated aromatic structure makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen pattern influences bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling rapid diversification of chemical libraries.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity halogenated intermediates.

Basic Information

Product Name	2-Bromo-5-Chloro-4-Fluorobenzaldehyde
CAS No.	1806838-88-9
Molecular Formula	C7H3BrClFO
Molecular Weight	237.45 g/mol
Synonyms	5-Chloro-2-bromo-4-fluorobenzaldehyde; 4-Fluoro-5-chloro-2-bromobenzaldehyde; 2-Bromo-4-fluoro-5-chlorobenzaldehyde; Benzaldehyde, 2-bromo-5-chloro-4-fluoro-; (2-Bromo-5-chloro-4-fluorophenyl)methanal; 1806838-88-9; 2-Br-5-Cl-4-F-C6H2CHO
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-4-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.