Description

2-Bromo-4-Fluoro-5-Nitro-Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its unique reactivity profile, offering three distinct points for chemical modification—the bromo, fluoro, and nitro substituents—which makes it an essential intermediate in advanced organic synthesis. It is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings.
• Nucleophilic Aromatic Substitution: The activated nitro and fluoro groups allow for selective displacement reactions to introduce diverse functionalities.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-Nitro-Benzaldehyde
CAS No.	1805556-76-6
Molecular Formula	C7H3BrFNO3
Molecular Weight	248.01 g/mol
Synonyms	5-Nitro-2-bromo-4-fluorobenzaldehyde; 2-Bromo-4-fluoro-5-nitrobenzaldehyde; Benzaldehyde, 2-bromo-4-fluoro-5-nitro-; 4-Fluoro-5-nitro-2-bromobenzaldehyde; 2-Bromo-4-fluoro-5-nitrobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-5-Nitro-Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.