Description

2-Bromo-4-Chloro-1,1'-Biphenyl is a halogenated biphenyl derivative, a versatile and high-purity organic intermediate essential for advanced chemical synthesis. Its precise molecular structure makes it a critical building block for constructing complex molecules in research and industrial applications. This compound is primarily sought by the pharmaceutical, agrochemical, and advanced materials sectors for use in cross-coupling reactions and as a precursor for functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the biphenyl core provides structural stability and bioactivity.
• Liquid Crystal & OLED Materials: Acts as a foundational unit in the production of advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Employed to introduce halogenated aromatic groups into polymer chains, enhancing flame retardancy, thermal stability, and other material properties.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D laboratories for constructing complex aromatic systems and exploring new synthetic methodologies.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.

Basic Information

Product Name	2-Bromo-4-Chloro-1,1'-Biphenyl
CAS No.	1805001-22-2
Molecular Formula	C12H8BrCl
Molecular Weight	267.55 g/mol
Synonyms	2-Bromo-4-chlorobiphenyl; 4-Chloro-2-bromobiphenyl; 1,1'-Biphenyl, 2-bromo-4-chloro-; Biphenyl, 2-bromo-4-chloro-; (2-Bromo-4-chlorophenyl)benzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-1,1'-Biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.