Description

1,4-Dibromo-2-Fluoro-3-Iodobenzene is a high-value, multi-halogenated aromatic building block designed for advanced synthetic chemistry. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty organic electronic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for organic semiconductors, liquid crystals (LCs), and other functional materials requiring precise halogen substitution.
• Cross-Coupling Reactions: An excellent substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the presence of bromine and iodine atoms with different reactivities.
• Chemical Synthesis: Employed in organic synthesis for sequential functionalization, enabling the selective introduction of other functional groups.
• Life Science Reagents: Used in the preparation of biochemical probes, fluorescent tags, and other research reagents.

Basic Information

Product Name	1,4-Dibromo-2-Fluoro-3-Iodobenzene
CAS No.	1804417-99-9
Molecular Formula	C6H2Br2FI
Molecular Weight	419.79 g/mol
Synonyms	2-Fluoro-1,4-dibromo-3-iodobenzene; 3-Iodo-1,4-dibromo-2-fluorobenzene; 1,4-Dibromo-2-fluoro-3-iodo-benzene; Benzene, 1,4-dibromo-2-fluoro-3-iodo-; 1804417-99-9
EINECS	Contact for details

Quality Control

Our 1,4-Dibromo-2-Fluoro-3-Iodobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.