Description

1,1,1-Trifluoro-Methanesulfonic Acid 5-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-Cyclohexen-1-Yl Ester is a specialized fluorinated sulfonate ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its unique fluorinated structure for enhanced biological activity or environmental stability.
• Advanced Material Synthesis: Serves as a precursor or monomer in the creation of specialty polymers and materials with tailored surface properties or reactivity.
• Cross-Coupling Reactions: Acts as an activated ester or leaving group in metal-catalyzed cross-coupling reactions, such as Suzuki or Negishi couplings, to form complex carbon-carbon bonds.
• Fluorine Chemistry: A valuable reagent for introducing trifluoromethanesulfonate (triflate) groups, which are excellent electrophiles and leaving groups in nucleophilic substitution reactions.
• Peptidomimetics & PROTACs: Employed in the synthesis of peptide analogs and Proteolysis Targeting Chimeras (PROTACs) due to its reactive ester functionality and potential for further derivatization.

Basic Information

Product Name	1,1,1-Trifluoro-Methanesulfonic Acid 5-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-1-Cyclohexen-1-Yl Ester
CAS No.	1803033-59-1
Molecular Formula	C13H18F3NO5S
Molecular Weight	357.35 g/mol
Synonyms	5-[(tert-Butoxycarbonyl)amino]-1-cyclohexen-1-yl trifluoromethanesulfonate; 1-Cyclohexen-1-ol, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1,1,1-trifluoromethanesulfonate; tert-Butyl N-[1-(trifluoromethylsulfonyloxy)cyclohex-3-en-1-yl]carbamate; Boc-Protected 5-Amino-1-cyclohexenyl Triflate; 5-(Boc-amino)-1-cyclohexenyl triflate; Trifluoromethanesulfonic acid 5-(Boc-amino)-1-cyclohexen-1-yl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. We adhere to strict in-process controls and final release specifications typical for high-value pharmaceutical intermediates, ensuring batch-to-batch consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.