Description

6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3H-[1,3]Oxazolo[4,5-B]Pyridin-2-One CAS NO 1802984-91-3 is a high-value, heterocyclic boronic ester derivative designed for advanced organic synthesis. This compound serves as a critical building block in pharmaceutical research and development, enabling the construction of complex molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronic ester coupling partner for the formation of carbon-carbon bonds, essential for constructing complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors, light-emitting materials, and other advanced functional materials.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery.

Basic Information

Product Name	6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3H-[1,3]Oxazolo[4,5-B]Pyridin-2-One
CAS No.	1802984-91-3
Molecular Formula	C13H17BN2O4
Molecular Weight	276.10 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-oxazolo[4,5-b]pyridin-2-one; 2-Oxo-2,3-dihydrooxazolo[4,5-b]pyridine-6-boronic acid pinacol ester; 6-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-[1,3]oxazolo[4,5-b]pyridin-2-one; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydrooxazolo[4,5-b]pyridin-2-one; Oxazolo[4,5-b]pyridin-2(3H)-one, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our production of 6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3H-[1,3]Oxazolo[4,5-B]Pyridin-2-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.