Description

2-Aminothiazole-5-Boronic Acid Pinacol Ester.Hcl is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science: Serves as a monomer or building block for creating novel polymers and functional materials.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and enzyme inhibitors for biological research.
• Ligand Synthesis: Useful for preparing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	2-Aminothiazole-5-Boronic Acid Pinacol Ester.Hcl
CAS No.	1802375-99-0
Molecular Formula	C9H16BN2O2S • HCl
Molecular Weight	262.57 g/mol (Free base: 226.11 g/mol)
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-amine hydrochloride; 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole hydrochloride; 2-Aminothiazol-5-ylboronic acid pinacol ester hydrochloride; 5-(Pinacolatoboryl)thiazol-2-amine HCl; ATBPE.HCl; 2-Amino-5-(pinacolboronato)thiazole hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Aminothiazole-5-Boronic Acid Pinacol Ester.Hcl is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.