Description

3-Chloro-4-Methoxy-5-Methylphenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing complex aromatic and heteroaromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific substituted biphenyl structures.
• Material Science Research: Serves as a precursor for constructing organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and other boron-containing functional molecules.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Chloro-4-Methoxy-5-Methylphenylboronic Acid Pinacol Ester
CAS No.	1801166-63-1
Molecular Formula	C₁₄H₂₀BClO₃
Molecular Weight	282.57 g/mol
Synonyms	3-Chloro-4-methoxy-5-methylbenzeneboronic acid pinacol ester; (3-Chloro-4-methoxy-5-methylphenyl)boronic acid pinacol ester; 2-(3-Chloro-4-methoxy-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Chloro-4-methoxy-5-methylphenyl-Bpin; B-(3-Chloro-4-methoxy-5-methylphenyl)pinacolboronate
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Methoxy-5-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC, to ensure high chemical purity and structural integrity, meeting the stringent requirements of research and process development. Certificates of Analysis (COA) with full characterization data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.