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(2-Isopropylindazol-5-Yl)Boronic Acid CAS NO 1801155-98-5


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CAS No.:1801155-98-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2-Isopropylindazol-5-Yl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry and pharmaceutical research. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and advanced material science, where precise carbon-carbon bond formation is required.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing indazole scaffolds.
  • Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile organoboron partner for palladium-catalyzed coupling with aryl/heteroaryl halides to form biaryl linkages.
  • Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
  • Material Science & OLED Development: Building block for creating organic electronic materials, including charge-transport layers and emissive materials in OLED devices.
  • Chemical Biology & Probe Synthesis: Utilized in the creation of molecular probes and inhibitors for studying biological pathways and enzyme functions.
  • Library Synthesis for Drug Discovery: Enables high-throughput parallel synthesis of diverse compound libraries for screening in hit identification and lead optimization campaigns.

Basic Information

Item Details
Product Name (2-Isopropylindazol-5-Yl)Boronic Acid
CAS No. 1801155-98-5
Molecular Formula C10H13BN2O2
Molecular Weight 204.04 g/mol
Synonyms 5-Borono-2-isopropyl-2H-indazole; 2-Isopropyl-1H-indazole-5-boronic acid; (2-Isopropyl-2H-indazol-5-yl)boronic acid; 2-Isopropyl-1H-indazole-5-boronic acid pinacol ester (protected form); B-(2-Isopropyl-2H-indazol-5-yl)boronic acid; 2-Isopropylindazole-5-boronic Acid; 2-Propan-2-yl-2H-indazole-5-boronic acid
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Quality Control

Our (2-Isopropylindazol-5-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-grade standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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