Description

6-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate featuring a pyridine core and a pinacol boronate ester functional group. This compound is a critical building block in modern medicinal chemistry, enabling the efficient synthesis of complex molecules through key cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for oncology and central nervous system (CNS) therapeutics.

Application

• Suzuki-Miyaura Cross-Coupling Reagent: A key boron-containing reagent for constructing carbon-carbon bonds in the synthesis of novel drug candidates and agrochemicals.
• Pharmaceutical Intermediate: Serves as a versatile building block in the research and development of potential Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target identification.
• Agrochemical Synthesis: A precursor in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Used in the synthesis of organic electronic materials and ligands for catalysts.

Basic Information

Item	Details
Product Name	6-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Amine
CAS No.	1800401-67-5
Molecular Formula	C12H19BN2O2
Molecular Weight	234.11 g/mol
Synonyms	5-Amino-6-methyl-3-pyridineboronic acid pinacol ester; 3-Amino-6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; (5-Amino-6-methylpyridin-3-yl)boronic acid pinacol ester; 6-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-amine; 3-Pyridinamine, 6-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 6-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.