Description

(2,4-Dichlorobenzyl)Boronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures. The pinacol ester group provides enhanced stability, making it a reliable reagent for demanding synthetic sequences.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require the 2,4-dichlorobenzyl moiety.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	(2,4-Dichlorobenzyl)Boronic Acid Pinacol Ester
CAS No.	1800284-57-4
Molecular Formula	C13H17BCl2O2
Molecular Weight	287.99 g/mol
Synonyms	2,4-Dichlorobenzylboronic Acid Pinacol Ester; Pinacol (2,4-Dichlorobenzyl)boronate; (2,4-Dichlorophenyl)methylboronic Acid Pinacol Ester; 4,4,5,5-Tetramethyl-2-[(2,4-dichlorophenyl)methyl]-1,3,2-dioxaborolane; B-(2,4-Dichlorobenzyl)boronic Acid Pinacol Ester; (2,4-Dichlorobenzyl)BPin; Boronic acid, B-[(2,4-dichlorophenyl)methyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our (2,4-Dichlorobenzyl)Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP for advanced intermediates and comply with global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.