Description

(2-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is a high-value, multifunctional boronic ester derivative that serves as a critical synthetic intermediate. Its core value proposition lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and advanced materials synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-purity building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the Suzuki reaction for efficient scaffold diversification.
• Material Science & OLED Development: Serves as a precursor for creating complex organic semiconductors, light-emitting materials, and charge-transport layers in organic light-emitting diodes (OLEDs) and other electronic devices.
• Ligand & Catalyst Design: Employed in the synthesis of specialized ligands for transition metal catalysis and as a precursor for novel organoboron catalysts.
• Chemical Biology & Probe Development: Utilized to create bioconjugates and molecular probes for studying biological processes and target engagement.
• Polymer Chemistry: Acts as a monomer or functionalization agent for introducing boronic ester handles into polymer backbones for advanced functional materials.

Basic Information

Product Name	(2-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol
CAS No.	1799974-98-3
Molecular Formula	C13H18BClO3
Molecular Weight	268.54 g/mol
Synonyms	2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanol; (2-Chloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol; 2-Chloro-5-(pinacolatoboryl)benzyl alcohol; (5-Chloro-2-(hydroxymethyl)phenyl)boronic acid pinacol ester; Pinacol (2-chloro-5-(hydroxymethyl)phenyl)boronate; B-(2-Chloro-5-(hydroxymethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1799974-98-3; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our (2-Chloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature: 2-8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.