Description

1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carbonitrile is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrrole or heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science: Serves as a precursor for organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) due to its functionalized pyrrole and boronate groups.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies via palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal complexation studies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carbonitrile
CAS No.	1799628-14-0
Molecular Formula	C12H17BN2O2
Molecular Weight	232.09 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-pyrrole-2-carbonitrile; 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-cyanopyrrole; 1-Methyl-4-(pinacolatoboryl)-1H-pyrrole-2-carbonitrile; 2-Cyano-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole; 1-Methyl-4-(pinacol boronate)-2-cyanopyrrole; 4-Pinacolatoboryl-1-methyl-1H-pyrrole-2-carbonitrile; Boronic acid, B-[2-cyano-1-methyl-1H-pyrrol-4-yl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to maintain stability and prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.