Description

2-(4-Bromo-2,6-Difluoro-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific halogenated, fluorinated aromatic structures.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for diagnostic and research applications.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic pathways.

Basic Information

Product Name	2-(4-Bromo-2,6-Difluoro-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	1799485-20-3
Molecular Formula	C12H14BBrF2O2
Molecular Weight	317.95 g/mol
Synonyms	4-Bromo-2,6-difluorophenylboronic acid pinacol ester; (4-Bromo-2,6-difluorophenyl)boronic acid pinacol ester; 2-(4-Bromo-2,6-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-2,6-difluorophenyl-Bpin; B-(4-Bromo-2,6-difluorophenyl)boronic acid pinacol ester; 1799485-20-3; Pinacol (4-Bromo-2,6-difluorophenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2,6-Difluoro-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as specified on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.