Description

(1R,2R)-Rel-N,n-Diethyl-2-(Hydroxymethyl)-1-Phenyl-Cyclopropanecarboxamide is a high-purity, stereochemically defined cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a rigid, functionalized cyclopropane scaffold into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used as a building block for developing new-generation pesticides and herbicides with enhanced stereoselective activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the study and development of new stereoselective catalytic reactions.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic chemistry and medicinal chemistry programs.
• Material Science: Potential monomer or additive for creating polymers with unique structural properties derived from the cyclopropane ring.

Basic Information

Product Name	(1R,2R)-Rel-N,n-Diethyl-2-(Hydroxymethyl)-1-Phenyl-Cyclopropanecarboxamide
CAS No.	1797131-72-6
Molecular Formula	C16H23NO2
Molecular Weight	261.36 g/mol
Synonyms	(1R,2R)-N,N-Diethyl-2-(hydroxymethyl)-1-phenylcyclopropane-1-carboxamide; rel-(1R,2R)-N,N-Diethyl-2-(hydroxymethyl)-1-phenylcyclopropanecarboxamide; (1R,2R)-Diethyl 2-(hydroxymethyl)-1-phenylcyclopropanecarboxamide; Phenylcyclopropane carboxamide derivative; Chiral cyclopropane carboxamide; Bicyclic lactam precursor
EINECS	Contact for details

Quality Control

Our (1R,2R)-Rel-N,n-Diethyl-2-(Hydroxymethyl)-1-Phenyl-Cyclopropanecarboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR, and mass spectrometry for structural confirmation, to ensure compliance with stringent in-house specifications. Certificates of Analysis (COA) documenting identity, purity, and chiral integrity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.