Description

Methyl 5-Chlorothiazole-4-Carboxylate is a high-purity heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex thiazole-based molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that leverage the thiazole moiety for bioactivity.
• Material Science Research: Serves as a precursor for functionalized heterocycles used in organic electronic materials and ligands for catalysis.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	Methyl 5-Chlorothiazole-4-Carboxylate
CAS No.	1784463-68-8
Molecular Formula	C5H4ClNO2S
Molecular Weight	177.61 g/mol
Synonyms	5-Chloro-4-(methoxycarbonyl)thiazole; Methyl 5-chloro-1,3-thiazole-4-carboxylate; 5-Chlorothiazole-4-carboxylic acid methyl ester; 4-Carbomethoxy-5-chlorothiazole; 5-Chloro-4-thiazolecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Chlorothiazole-4-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, GC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.