Description

2-Oxabicyclo[2.1.1]hexane-4-carboxylic acid is a high-value, synthetically versatile bicyclic building block. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting complex, bridged ring systems.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science: Serves as a precursor for specialty polymers and advanced materials requiring rigid, oxygen-containing bicyclic structures.
• Chemical Biology & Probe Development: Utilized as a scaffold or linker in the design of molecular probes and biochemical tools.
• Academic & Industrial R&D: Employed in methodological development and exploratory synthesis to access new chemical space.
• Chiral Synthesis: Potential use as a building block for introducing chirality and conformational constraint into target molecules.

Basic Information

Product Name	2-Oxabicyclo[2.1.1]hexane-4-carboxylic Acid
CAS No.	1784145-36-3
Molecular Formula	C6H8O3
Molecular Weight	128.13 g/mol
Synonyms	2-Oxabicyclo[2.1.1]hexane-4-carboxylic acid; 4-Carboxy-2-oxabicyclo[2.1.1]hexane; Bicyclo[2.1.1]hexane-4-carboxylic acid, 2-oxa-; 2-Oxa-bicyclo[2.1.1]hexane-4-carboxylic acid; 1-Oxa-4-carboxybicyclo[2.1.1]hexane (tautomeric form); OBCA (abbreviation); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-Oxabicyclo[2.1.1]hexane-4-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.